Nano Science and Technology Institute
Nanotech 2005 Vol. 3
Nanotech 2005 Vol. 3
Technical Proceedings of the 2005 NSTI Nanotechnology Conference and Trade Show, Volume 3
Chapter 10: Computational Methods, Numerics and Software Tools

Ion Sources for Biomolecules with Controlled Superposition of Electric and Pneumatic Fields

Authors:A. Hieke
Affilation:Ciphergen Biosystems, Inc., US
Pages:648 - 651
Keywords:MALDI, proteomics, ion source, ion temperature, collisional cooling, GEMIOS, ANSYS, simulation
Abstract:As previously reported the design of advanced ion sources for collisionaly cooled biomolecules required the development of an advanced multi-physics simulation system GEMIOS (Gas and Electromagnetic Ion Optical Simulator). Recent research based on such GEMIOS simulations led to the creation of the term "electro-pneumatic ion optics" since the functionality of considered novel ion-optical devices is in fact based on the superposition of at least two vector fields and one scalar field. Specifically, and in contrast to state-of-the art devices, gas pressure and gas flow velocities are not considered as global quantities but true field solutions are obtained. As a result, collision frequencies and momentum transfer vary spatially. This allows the design a of new class of electro-pneumatic devices in which elements act as electrodes as well as nozzles or wings and in which the balance between electrical and collisional forces varies locally in a controlled fashion.
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