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 | Nanotech 2005 Vol. 2
Technical Proceedings of the 2005 NSTI Nanotechnology Conference and Trade Show, Volume 2
Chapter 7: NEMS and MEMS Fabrication |
| | Microfabricated Silicon Apertures for Ion Channel Measurement | | Authors: | S.J. Wilk, M. Goryll, L. Petrossian, G.M. Laws, S.M. Goodnick, T.J. Thornton, M. Saraniti, J.M. Tang and R.S. Eisenberg | | Affilation: | Arizona State University, US | | Pages: | 504 - 507 | | Keywords: | ion channels, microfabrication, membranes | | Abstract: | Ion channels are proteins that act as pores in cell membranes and allow only specific ions to pass through the cell wall. Here, we present a method for microfabrication of apertures in a silicon substrate using well-known cleanroom technologies. Apertures were etched through a silicon wafer using a plasma-etcher and then rendered hydrophobic with chemical vapor deposition of a Teflon surface layer. Characteristic measurements showing physiological single channel gating behavior of OmpF porin and alpha-hemolysin channel proteins have been made. | | ISBN: | 0-9767985-1-4 |
| Pages: | 808 |
| Hardcopy: | $165.00 |
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