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 | Nanotech 2005 Vol. 1
Technical Proceedings of the 2005 NSTI Nanotechnology Conference and Trade Show, Volume 1
Chapter 7: DNA, Protein, Cells and Tissue Arrays |
| | Enhancement of DNA Microarray Hybridization using Shear-Driven Microfluidics | | Authors: | J. Vanderhoeven, K. Pappaert, B. Dutta, P. Vanhummelen, G.V. Baron and G. Desmet | | Affilation: | Free University of Brussels, BE | | Pages: | 343 - 346 | | Keywords: | microarray, hybridization, microfluidics, shear-driven | | Abstract: | On microarrays the transport of the target molecules towards the spots only occurs by molecular diffusion. As a result, microarray analyses require overnight incubation and are highly inefficient in terms of capture rate and detection limit. To overcome this diffusion limitation, several solutions have already been proposed: electrokinetic flows, ultra-sound mixing, pump-around systems, etc…. The present study demonstrates how DNA microarray analysis is enhanced by miniaturization. Only a small sample volume ( | | ISBN: | 0-9767985-0-6 |
| Pages: | 844 |
| Hardcopy: | $165.00 |
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