Nano Science and Technology Institute
Nanotech 2005 Vol. 1
Nanotech 2005 Vol. 1
Technical Proceedings of the 2005 NSTI Nanotechnology Conference and Trade Show, Volume 1
 
Chapter 6: Bio Nano Materials
 

Phosphorylcholine-protected Nanoparticles Functionalized with Both Magnetic and Photoluminescent Properties

Authors:Y.C. Chung and C.J. Chen
Affilation:National University of Kaohsiung, TW
Pages:320 - 323
Keywords:nanoparticle, biocompatible, endocytosis
Abstract:We prepared the magnetite core coated with nano-graded ZnS shell to display superparamagnetic and photoluminescent properties. By adsorbing the phosphorylcholine-ended thiol to stabilize the core-shell nanoparticles, the particles can be well-dispersed in aqueous buffer solution for a long term and display weak interaction with proteins. The superparamagnetic magnetite was synthesized using ferric chloride and sodium sulfite mixture and gathered via magnetic precipitation and centrifugation. The magnetite pre-adsorbed with zinc acetate overnight was then dispersed and reacted with thioacetamide using ultrasonic horn (100 W, Branson) in deionized water at 80 °C for 3 h, giving the thin zinc sulphide layer. Furthermore, the phospholipid derivative, 11-mercaptoundecylphosphorylcholine (SPC), derived from our previous investigation was to stabilize the outmost ZnS surfaces of nanoparticles.
Phosphorylcholine-protected Nanoparticles Functionalized with Both Magnetic and Photoluminescent PropertiesView PDF of paper
ISBN:0-9767985-0-6
Pages:844
Hardcopy:$109.95
 
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