Nanotech 2001 Vol. 1
Nanotech 2001 Vol. 1
Technical Proceedings of the 2001 International Conference on Modeling and Simulation of Microsystems

Characterizaton, Parameter Extraction, Calibration Chapter 8

Direct Write Technology as a Tool to Rapidly Prototype Patterns of Biological and Electronic Systems

Authors: B.R. Ringeisen, D.B. Chrisey, A. Piqué, D. Krizman, M. Brooks and B. Spargo

Affilation: Naval Research Laboratory, United States

Pages: 414 - 417

Keywords: direct write, microfluidic device, pluripotent cells, protein microarray, rapid prototyping

Abstract:
The full potential of modeling and simulations is only realized when it is based on experimental results under varied conditions and systems. A single tool to rapidly prototype electronic and biological circuits would enhance the understanding and application of many systems. We have developed a novel laser-based direct write technique which has sub-10 micron resolution and is capable of rapidly prototyping micron-scale passive electronic devices, patterning active biological materials, and micro-machining conformal, flexible, and planar substrates. This manuscript presents our recent efforts to fabricate a living microfluidic device comprised of patterned and differentially cultured pluripotent cells, and to construct an improved antibody microarray capable of rapid and efficient protein identification (proteomics) from malignant and healthy cells.


ISBN: 0-9708275-0-4
Pages: 638

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