| |
 | Nanotech 2001 Vol. 2
Technical Proceedings of the 2001 International Conference on Computational Nanoscience and Nanotechnology
Chapter 2: Bioinformatics/Mathematical Biology |
| | Simulation Studies of Channels in Biological Membranes | | Authors: | D. Henderson, D.D. Busath, R.L. Rowley, P.S. Crozier and D. Boda | | Affilation: | Brigham Young University, U.S.A. | | Pages: | 45 - 48 | | Keywords: | ion channels, biomembranes, selectivity, conductance, simulations, electrolytes | | Abstract: | The results of our recent studies of the selectivity of a calcium channel by means of a Monte Carlo simulation and of the conductance of ions in a model channel by means of a molecular dynamics simulation are reported. In our selectivity study we find that as a result of the charge and confined space within the channel, Ca++ ions are preferred over Na+ ions because of their ability to deliver twice the charge using about the same excluded volume. In our conductance study, the simulation is run in parallel for a total of 100 ns for each condition of concentration and applied potential. For a 1 M NaCl solution with SPC/E water using a moderate applied voltage, 12 Na+ and no Cl- ions pass through the channel. The voltage drop across the channel and the conductance are reported. |  | View paper | | ISBN: | 0-9708275-3-9 |
| Pages: | 218 |
| Hardcopy: | $100.00 |
| Special: | 3 CD Set — 15% off with Free Shipping |
| Up | |
|
| nanoPRwire™ |
 |
| News Headlines |
 |
|
|
| |
| |
|
| | |
| |
|
|
