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Research Team at Northeastern University One Step Closer to Developing Precise Nanoparticle Drug Delivery System

Led by Distinguished Professor and Chair of Pharmaceutical Sciences Mansoor Amiji, his self-defined smart luggage system effectively attacks tumor cells, not healthy ones

In the release, researchers at Northeastern conducted their study under “the condition that tumor cells that grow in low-oxygen environments convert glucose into lactic acid, which makes cancer cells more drug resistant and harder to treat with chemotherapy.” What makes the nanoparticle drug so effective is administering small doses of the anticancer drugs directly to the tumors using a nanoparticle drug combination of lonidamine and the chemo agent paclitaxel.

The research of Dr. Amiji and his team was funded by a 5 year, $2M US+ from the National Cancer Institute’s Alliance for Nanotechnology in Cancer program. Next steps for the research and nanoparticle drug delivery system include rigorous testing for safety and clinical trials.

NWN Note: Dr. Mansoor Amiji has been a lead speaker at NSTI Nanotech for more than a decade. Dr. Amiji also serves as a Co-Instructor for the annual One-Day Short Course Nanotechnology for Medical Diagnostics and Treatment with Dr. Srinivas Iyer, Los Alamos National Laboratory.

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