Cell separation by paramagnetic and diamagnetic forces
P. Stephen Williams
P. Stephen Williams, Ph.D., is a Staff Scientist in the Department of Biomedical Engineering, Lerner Research Institute of the Cleveland Clinic (CC), and Assistant Professor in the Department of Molecular Medicine of the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University (CWRU), Cleveland, Ohio. He received his B.Sc. degree (Chemistry and Computer Science, 1975) and Ph.D. (Chemistry, 1980) from the University of Wales, Swansea, UK. His research is focused in the area of separation science, with emphasis on the various forms of field-flow fractionation (FFF) and split-flow thin channel (SPLITT) separation. He works in the Cell Separation Research Laboratory, directed by Maciej Zborowski, Ph.D. This laboratory is devoted to research and development of instrumentation for fast cell sorting, in particular, magnetic cell sorting. This requires application of fine magnetic particles (nanoparticles) for cell tagging and strong magnetic fields and gradients to sort the tagged cells.