Laser “microexplosions” of phthalocyanine nanoparticles in tumor

B.Y. Kogan, A.A. Pankratov, A.V. Butenin, R.A. Feyzulova, Y.B. Zolotavkina, R.I. Yakubovskaya, V.M. Negrimovsky, E.A. Luk’yanets, G.N. Vorozhtsov
FGUP “GNC “NIOPIK”, RU

Keywords: Cancer Prevention, Diagnosis and Treatment

Abstract:

Light-absorbing nanoparticles (NPs) incorporated in a tissue can be heated by short-pulse laser irradiation up to several thousand Kelvin degrees. Average tissue temperature may be kept normal if average fluence rate is low. Earlier we have reported tumor growth inhibition using powerful pulse laser irradiation of carbon and gold NPs in tumor [1,2]. In presented work an antitumor effect of phthalocyanine NPs under laser irradiation in tumor blood vessels has been studied.