Relaxation Time Constants of Nanometals in Human Tissues and Clinical Applications
R. Sharma, A. Sharma
Center of Nanotechnology, IN
Keywords: picotechnology, pico fluorescein spectrometer, HIV, nitric oxide, mercury, lead
Abstract:The metals are in abundance in human body in biofluids, blood, cerebrospinal fluid, saliva, lymph. These metals are found in free and bound forms in each tissue and their amount is tissue specific. The mechanism of major metals and their binding affects their nuclear magnetic resonance relxation times. The longitudinal relaxation (T1) and transverse (T2) time constants are unique signatures in detection and classifying major soft tissue cancers or tissue diseases. We developed a data base of relaxivities of normal and diseased human tissues both soft and solid types. The evaluation of relaxation behavior of major human tissue diseases was made and relaxation time constants of human tissues were measured. The database of tissues is helpful as cheaper technology for quicker tissue characterization. The database also useful in imaging suits as reference guide. In conclusion, database of human tissue tumors and human fluid T1 and T2 relaxation times was developed based on nanometal NMR relaxation signatures.