Advances in Bio imaging using the nanoparticulate contrast systems
C. Ng, Y. Pathak
Sullivan University College of Pharmacy, US
Keywords: nano systems for bio imaging, imaging, nanoparticles contrast systems
Abstract:Recent developments in the contrast agents being used in Bio imaging especially the development of nanoparticulate contrasting agents has opened many new vistas in this field. Bio imaging is extensively used to characterize the particle distribution and accumulation in bio systems. The nano sized contrast systems offering an excellent tool to understand biological process at molecular levels. This is also helping in the development of nano diagnostic tools and innovative drug delivery systems and its evaluation in bio systems. Several nanoparticulate contrast systems like quantum dots, gold nano particles, and dye doped silica nano particles have offered better photo stability, higher quantum yield and in vitro, in vivo stability as compared to the conventional contrast dyes. Multi modality nano particulate systems are another area which can be used across multiple imaging platforms with optical, MRI, CT and positron emission tomography imaging. The presentation will review the recent developments in nanoparticulate contrast imaging agents and its potential applications in bio imaging.