The Molecular Foundry at Lawrence Berkeley National Laboratory is a User Facility charged with providing support to research in Nanoscience underway in academic, government and industrial laboratories around the world. The Foundry provides users with instruments, techniques and collaborators to enhance their studies of the synthesis, characterization and theory of nanoscale materials. Its focus is on the multidisciplinary development and understanding of both “soft” (biological and polymeric) and “hard” (inorganic and microfabricated) nanostructured building blocks and the integration of those building blocks into complex functional assemblies. The Molecular Foundry houses six facilities and offers access to a variety of affiliated laboratories in support of users as well as the inhouse research programs. Users are invited to submit proposals requesting free access to the state-of-the-art instruments and techniques, and to the highly skilled staff.