2008 NSTI Nanotechnology Conference and Trade Show - Nanotech 2008 - 11th Annual

Partnering Events:

TechConnect Summit
Clean Technology 2008

Amphoteric liposomes are a platform for multi-organ delivery of oligonucleotides

C. Reinsch, U. Rauchhaus, S. Panzner
novosom AG, DE

Keywords:
siRNA, delivery, in vivo, liposomes

Abstract:
Oligonucleotides (ONs) such as antisense (ASO) or siRNA have created a need for new technologies that further enable the systemic and targeted delivery of these active principles. Here, we describe amphoteric, fully charge-reversible liposomes as a novel carrier concept that overcomes the limitations in biodistribution of cationic vectors systems while keeping functionality.


Nanotech 2008 Conference Program Abstract