2008 NSTI Nanotechnology Conference and Trade Show - Nanotech 2008 - 11th Annual

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TechConnect Summit
Clean Technology 2008

Permeability and protein separations: functional studies of porous nanocrystalline silicon membranes

J. Snyder, M. Kavalenka, D. Fang, C. Striemer, P. Fauchet, J. McGrath
University of Rochester, US

Keywords:
nanomembranes, protein separations

Abstract:
We have developed an ultrathin (15nm) freestanding nanoporous silicon based membrane [1]. This new material, termed porous nanocrystalline silicon (pnc-Si), is fabricated using standard photolithography techniques. Pore sizes can be tuned in a thermodynamically driven self-assembly step during pnc-Si manufacture. The intrinsic characteristics of this new material and its relatively facile fabrication make it superior to commercial membranes and other currently studied nanomembranes. Pnc-Si air and water flow rates are an order of magnitude higher than those reported of carbon nanotube membranes and commercial track etched membranes. We have employed pnc-Si membranes in protein separations, and because of the well defined pores, observe sharp molecular weight cutoffs of complex protein mixtures. Additionally we have used pnc-Si membranes to perform blood protein separations, and have observed separations by diffusion alone that are difficult for standard hemodialysis membranes to achieve.


Nanotech 2008 Conference Program Abstract