A broad-spectrum viricide and its application as a novel human anti-viral therapeutic system

Keywords:
nanomedicine, antivirals, therapeutics, H5N1

Abstract:
A new class of therapeutic anti-virals has been created utilizing the principles of nanotechnology. A broad-spectrum targeting molecule (ligand) is chemically attached to a polymer-derived nano-structure. Attachment to the viral particle via the sialic acid attachment system is accomplished. The envelope of the targeted viral particle is then destroyed. The now non-infectious genomic material escapes and is then destroyed by the cells of the immune system. Studies have been performed on animals infected with rabies, H5N1, human influenza, HIV, dengue, Ebola and the virus that causes epidemic keratoconjunctivitis. These studies have been done by various US government medical research agencies. Results of these studies and their implications for human anti-viral treatments will be discussed

Nanotech 2008 Conference Program Abstract