2008 NSTI Nanotechnology Conference and Trade Show - Nanotech 2008 - 11th Annual

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TechConnect Summit
Clean Technology 2008

How much advantage do Nanoscale Phenomena afford for Pulmonary Delivery?

N. Walji, M. Thanou, N. Quirke
Imperial College London, UK

Keywords:
nanoparticle, diffusion, biological barriers, multiple particle tracking

Abstract:
Although claims of improved performance due to nanoscale phenomena are made on a daily basis, exactly how much advantage can be afforded by nanotechnology for specific medical applications is quantitatively unknown. It is generally suggested that the smaller the size the better the targeting and distribution effect, however the exact relationship between nanoparticle size and diffusivity through biological membranes is unknown. Diffusivity has traditionally been related to particle size via the Stoke-Einstein equation, which states that diffusion is inversely proportional to particle radius. It has been hypothesized that nanoscale effects, acting on particles


Nanotech 2008 Conference Program Abstract