2008 NSTI Nanotechnology Conference and Trade Show - Nanotech 2008 - 11th Annual

Partnering Events:

TechConnect Summit
Clean Technology 2008

Site-Directed Chemical Modification of Phage Particles

C.J. Noren
New England Biolabs, US

Keywords:
site-directed chemical modification, phage particles

Abstract:
Diverse composition of surface amino acid in filamentous phages allows running various chemical reactions on their surfaces to produce nanomaterials with new specific properties: fluorescent, biotin-, or radioactively labelled, cytotoxic, etc. Phage can be used also for conjugation of organic ligands to obtain genetically encoded organic libraries, can be labelled with gold nanobeads to obtain laser-activated therapeutics, conjugated with anticancer drugs to target them to the site of disease, etc. The report will discuss the reactivity and modification of phage particles.


Nanotech 2008 Conference Program Abstract