2008 NSTI Nanotechnology Conference and Trade Show - Nanotech 2008 - 11th Annual

Partnering Events:

TechConnect Summit
Clean Technology 2008

Mathematical Model of effect of drug delivery on blood flow in external magnetic field by Magnetic Nanoparticles

S. Mishra, V.K. Katiyar, V. Arora
Indian Institute of Technology Roorkee, IN

Keywords:
magnetic nanoparticles, capillary, blood flow, magnetic force, nano-drug targeting

Abstract:
Magnetism is one of the major contributors in biological and biomedical research. Efficient drug targeting is vital for the medical treatment of various diseases. In magnetically targeted therapy, a cytotoxic drug is attached to a biocompatible magnetic nanoparticle carrier. These drug/carrier complexes are injected into the patient via the circulatory system. When the particles have entered the blood stream, external, high-gradient magnetic fields are used to concentrate the complex at a specific target site within the body. A mathematical model is proposed to study the velocity profiles i.e. velocity of magnetic nanoparticles (diameter 20 nm) as drug carrier and blood in the presence of uniform external magnetic field inside the capillary region. The volumetric flow rate and skin friction are also taken into account and the analytic expressions are also developed.


Nanotech 2008 Conference Program Abstract