2008 NSTI Nanotechnology Conference and Trade Show - Nanotech 2008 - 11th Annual

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TechConnect Summit
Clean Technology 2008

Analysis of mechanical characterization on microneedles for fluid sampling and drug delivery

P. Zhang, R. Zhang, G.A. Jullien
University of Calgary, CA

Keywords:
microneedle array, buckling analysis, BioMEMS

Abstract:
Out of Plane, Side Opened, Robust MEMS Microneedle Arrays was modeled, designed and simulated. The microneedle array was fabricated by employing a bi-mask technique, which allows for needle top structures to be easily implemented, to facilitate sharp tips, a cylindric body and side ports which minimize the potential for clogging. The mechanical properties of the microneedle for in-vivo fluid sampling and drug delivery were theoretically analyzed including analysis of fracture strength and distribution of von mises stress. The conditions of initial insertion and after initial insertion were considered. The detail buckling analyses on needle structure were also presented. Two modes of buckling were come to and discussed. It is shown that the needle tip is not the weakest for needle structure and the microneedle is robust enough to withstand the stress generated during insertion.


Nanotech 2008 Conference Program Abstract