2007 NSTI Nanotechnology Conference and Trade Show - Nanotech 2007 - 10th Annual

Specific targeting and delivery of virus envelope-coated nanoparticle cargoes into receptor-bearing cells and subcellular compartments.

A.C. Moore, A.A. Kolokoltsov and R.A. Davey
University of Texas Medical Branch, US

Keywords:
virus, cell targeting, membrane penetration, drug delivery

Abstract:
We build on our recently reported work in Nano letters describing coating of nanoparticle cargoes with virus envelope proteins to show that the method works for viruses other than ecotropic murine leukemia viruses. We also track the virus-envelope coated nanoparticles into cells using real-time microscopy on live cells. We discuss the potential benefits of using this method to target drugs to specific cells and subcellular compartments.

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Nanotech 2007 Conference Program Abstract

 
 

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