2007 NSTI Nanotechnology Conference and Trade Show - Nanotech 2007 - 10th Annual

Noise-Differential Based Detection of Cells on a Microelectronic Sensor/Actuator Array

N. Manaresi, F. Lanzetta, A. Romani, G. Medoro and R. Guerrieri
Silicon Biosystems spa, IT

Keywords:
optical sensors, microelectronics, cells, dielectrophoresis, noise

Abstract:
We present a new method to count cells on a microelectonic lab-on-a-chip integrating an array of Dielectrophoretic (DEP) cages and embedded optical sensors. Cells are trapped by DEP cages above photodiodes measuring the optical near field. The presence of cells is measured indirectly by the increase in noise power in sensors underlying cells. Compared to previously methods, this approach, achieves a 0% error on experimental test runs with 100 cages. The method is inherently insensitive on spatial gradients of illumination and on Fixed Pattern Noise from the embedded photdiodes array. This approach opens up the possibility to count cells in a flow-less portable system without complex external optical add-ons or microscopes.

Back to Program

Sessions Sunday Monday Tuesday Wednesday Thursday Authors Keywords

Nanotech 2007 Conference Program Abstract

 
 

Names, and logos of other organizations are the property of those organizations and not of NSTI.
This event is not open to the general public and NSTI reserves the right to refuse admission and participation to any individual.