2007 NSTI Nanotechnology Conference and Trade Show - Nanotech 2007 - 10th Annual

Electrospinning Cellulose Nitrate Nanofibers for Biosensor Applications

S. Nartker, S. Daugherty, P. Satoh, M. Misra and L.T. Drzal
Michigan State University, US

Keywords:
electrospinning, biosensor, cellulose nitrate, nanofiber

Abstract:
Electrospinning is a unique way to produce novel polymer nanofibers with diameters typically in the range from 10 nm to 1500nm. Nanofibers can be made from a variety of solutions or melts. Cellulose Nitrate nanofibers with controlled diameters of 350 nm to 1200 nm were prepared by altering the polymer concentration from 6 wt% to 10 wt%. The solvent used was a 70:30 mixture of ethanol : acetone. This mixed solvent was used to modify the vapor pressure and surface tension, which affect the electrospinning process. It was found in this study that needle gauge, separation distance and solution flow rate do not significantly impact the fiber diameter. Fibers were also controlled to obtain aligned and patterned structures. Fiber morphological characterizations were performed using an Environmental Scanning Electron Microscope (ESEM). The nanofibers produced will be used as membrane materials in biosensor devices. Preliminary data shows that the electrospun cellulose nitrate fibers offer an improved surface area and can therefore bind more protein than their commercial counterparts. This study established the dominant factor for controlling fiber size; solution viscosity, and will continue by analyzing the effect of fiber size and alignment on biosensor performance.

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Nanotech 2007 Conference Program Abstract

 
 

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