2007 NSTI Nanotechnology Conference and Trade Show - Nanotech 2007 - 10th Annual

F0F1-ATPase as biosensor and applications

yue jiachang
institue of biophysics,CAS, CN

Keywords:
biosensor

Abstract:
The new significant accomplishment in our researches: (1) one of brand new biosensors (immuno-rotary biosensor) of F0F1-ATPase within chromatophore was constructed. The Capture of pathogen was based on antibody‚Äďantigen reaction. The detection of pathogen based on proton flux rate change driven by ATP-synthesis of F0F1-ATPase, which was indicated by fluorescence Qdots in chromatophores. (2) This biosensor extended for rapid, selective, sensitive applications of not only for the virus, proteins (CRP), bacterium, and molecular hapten clenbuterol but also the miRNA, with their recognized. 3 Qdots as smart pH meter and optical code for the biosensor.

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