2007 NSTI Nanotechnology Conference and Trade Show - Nanotech 2007 - 10th Annual

Chitosan-Nanoparticle as UV Filter and Carrier for Cosmetic Actives

S.P. Wanichwecharungruang
Assoc. Prof., TH

Keywords:
nanoparticles, chitosan, encapsulation, cosmetic actives, UV filter

Abstract:
Chitosan derivative was prepared by grafting both phthaloyl groups and methoxy poly(ethylene glycol) moieties onto the polymer chain. Nanoparticles of the prepared chitosan derivative were then obtained through solvent displacement technique. The products are stable white particles with the average sizes of about 40-150 nm (dry particle) as shown by scanning electron microscopy (SEM) and transmission electron microscopy (TEM). Various cosmetic actives such as octyl methoxycinnamate, ascorbyl palmitate (vitamin C derivative) and astaxanthin could be successfully encapsulated into these chitosan-nanoparticles. UV screening property, antimicrobial activity and stability of the particles were investigated. Photostability of selected encapsulated cosmetic active was also compared to the un-encapsulated active.

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