2007 NSTI Nanotechnology Conference and Trade Show - Nanotech 2007 - 10th Annual

Vertically Aligned Carbon Nanofiber Array for Biosensing and Cell Stimulation

J. Li, T.D.B. Nguyen-Vu, H. Chen, A.M. Cassell, J.E. Koehne, R.J. Andrews and M. Meyyappan
NASA Ames Research Center, US

Keywords:
carbon nanofiber array, DNA sensor, cell stimulation, biomedical device

Abstract:
It is of great fundamental interests to develop micro- and nano- devices that can interface with biological systems at the subcellular level for both sensing and modulation. Electrochemical methods are of particular advantages in converting biological information into electrical signals and thus widely employed in biomedical applications. Nanotechnology provides new approaches to improve the performance of conventional electrodes through miniaturizing the electrode size or incorporating with nanostructured materials. Here we report on our recent work on the development of vertically aligned carbon nanofiber (VACNF) arrays for biosensing and cell stimulation. CNFs and carbon nanotubes belong to a family of tube-like carbon nanomaterials with unique electronics and materials properties. We have developed a plasma enhanced chemical vapor deposition process to grow VACNFs selectively on patterned electrical circuits. The VACNFs are highly conductive metallic wires with a high-aspect ratio and a diameter comparable to biomolecules. Hence, they can serve as nanoelectrodes to link microelectronic circuits with biomolecules such as DNA/RNA and proteins for electronic biosensing, or with cells/tissues as an implanted device for programmable electrical stimulation and recording. We will demonstrate approaches to fabricate, integrate, encapsulate, and functionalize VACNF arrays for different biomedical applications toward diagnosis, functional electrical stimulation, and neuroprosthesis.

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Nanotech 2007 Conference Program Abstract

 
 

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