Nanotechnology Conference and Trade Show - Nanotech 2006
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Technical Conferences
Confirmed Speakers
Nano Electronics & Photonics
Nano Fabrication
MEMS & NEMS
Sensors & Systems
Micro & Nano Fluidics
MSM - Modeling Microsystems
WCM - Compact Modeling
Nanostructured Materials & Devices
Soft Nanotechnologies & Applications
Polymer Nanotechnology
Carbon Nano Structures & Devices
Nano Particles & Applications
Composites & Interfaces
Energy Technologies & Applications
Environment & Society
ICCN - Nanoscale Modeling
Nanoscale Characterization
National Security Applications
Bio Nano Materials & Tissues
Bio Sensors & Diagnostics
Biomarkers & Nanoparticles
Cancer Diagnostics, Imaging & Treatment
Cellular & Molecular Dynamics
Computational Modeling in Life Sciences
Drug Delivery & Therapeutics
Imaging
Nano Medicine
Nanotech to Neurology
Clean & Controlled Environments
TechConnect Summit - IP Matchmaking
Industrial Impact Workshop
Program Committee

Conference Proceedings

Conference Technical Proceedings

2006 Symposium on

Nanotechnology for Cancer Prevention, Diagnosis and Treatment

CancerNano 2006

Cancer Diagnostics, Imaging & Treatment

May 7 - 11, 2006
Hynes Convention Center
Boston, Massachusetts, U.S.A

Symposium sponsors

National Cancer Institute National Institutes of Health

Symposium Chairs

Mansoor Amiji Mansoor Amiji
Department of Pharmaceutical Sciences,
Northeastern University, USA
Vladimir Torchilin Vladimir Torchilin
Bouvé College of Health Sciences,
Northeastern University, USA

Symposium Keynotes

Judah Folkman Challenges in Cancer Prevention, Diagnosis, and Treatment
Judah Folkman,
Children’s Hospital Boston, USA, (speaker biography)
Rakesh K. Jain Delivery of Nano-medicine to Solid Tumors: Role of Tumor Physiology
Rakesh K. Jain,
Massachusetts General Hospital, Harvard Medical School, USA, (speaker biography)

Confirmed Speakers

Esther H. Chang Nanodelivery: Materializing the Potential of Cancer Molecular Medicine
Esther H. Chang
Georgetown University Medical Center, USA, (speaker biography)
Dennis E. Discher Novel Nanostructures for Tumor-Targeted Delivery
Dennis E. Discher
University of Pennsylvania, USA, (speaker biography)
Vladimir Torchilin Targeted Drug Delivery in Cancer
Vladimir Torchilin
Bouvé College of Health Sciences,
Northeastern University, USA
Sangeeta Bhatia Multifunctional Nanoparticles in Cancer Therapy
Sangeeta Bhatia
MIT, Brigham & Women’s Hospital, USA, (speaker biography)
James Basilion Molecular Imaging in Cancer
James Basilion, Associate Professor, Department of Biomedical Engineering
Case Western Reserve University, US, (speaker biography)

NCI/NSTI Special Panel Discussion

Translation of Cancer Nanotechnology — From Bench to Bedside

Boston, MA (May 7 - 11, 2006)
Tuesday, May 9th Tentative Agenda

  • NCI Nanotechnology for Cancer Alliance
    Piotr Grodzinski, National Cancer Institute
  • Role of Nanotechnology Characterization Laboratory
    Scott McNeil, NCI Nanotechnology Characterization Laboratory Director
  • Role of National Institute of Standards and Technology
  • Nanotechnology and the FDA

Symposium Sessions

 

Monday May 8

4:00 Cancer Nanotech - 1
6:00 Poster Session 1 and Nanotech Exhibit Reception hosted by Advance Nanotech, booth #903
 

Tuesday May 9

8:30 Keynote - Nanotechnology for Cancer Prevention, Diagnosis and Treatment
10:30 Cancer Prevention, Diagnosis and Treatment through Nanotech
1:30 Cancer Prevention, Diagnosis and Treatment through Nanotech
3:30 Nanotechnology for Cancer Prevention, Diagnosis and Treatment
4:00 Poster Session 2 and Nanotech Exhibit Reception hosted by Feinstein Kean Healthcare, booth #716
 Cancer Nanotech -3
6:00 Translation of Cancer Nanotechnology - From Bench to Bedside (Panel)
 

Wednesday May 10

10:30 Cancer Nanotech - 2
1:30 Nanotechnology for Drug Delivery
4:00 Nanotech for Neurology
4:00 Characterization: Drug Delivery
6:00 Poster Session 3 and Reception
 Characterization: Drug Delivery
 Drug Delivery
 Cellular and Molecular Dynamics
 Imaging
 

Thursday May 11

 

Symposium Program

 

Monday May 8

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4:00 Cancer Nanotech - 1Room 207
 Session chair: Travis Earles, National Cancer Institute
4:00 Nano-Mesosphere Drug Carriers for Localized Cancer Chemotherapy
E.P. Goldberg, B.A. Almond, A.R. Hadba, B.J Cuevas, A. York, I. Enriquez, University of Florida, US
4:20 Temperature-Triggered Nanotechnology for Chemotherapy: Rapid Release From Lysolipid Temperature-Sensitive Liposomes
J.K. Mills and D. Needham, Duke University; presently Sterne, Kessler, Goldstein & Fox, P.L.L.C., US
4:40 Role of immunoregulators as possibility of tumor hypoxia-induced apoptosis
R. Sharma, S. Kwon and C.J. Chen, Columbia University, US
5:00 Modulation of Intracellular Ceramide using Polymeric Nanoparticles to Overcome Multidrug Resistance in Tumor Cells
L.E. van Vlerken, D. Shenoy, Z. Duan, M. Seiden, S. Mehta and M.M. Amiji, Northeastern University, US
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6:00 Poster Session 1 and Nanotech Exhibit Reception hosted by Advance Nanotech, booth #903Expo Hall
 

Tuesday May 9

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8:30 Keynote - Nanotechnology for Cancer Prevention, Diagnosis and TreatmentHall D
 Session chair: Mansoor Amiji, Northeastern University
8:30 Challenges in Cancer Prevention, Diagnosis, and Therapy (invited)
J. Folkman, Children’s Hospital Boston, US (speaker biography)
9:15 Delivery of Nano-medicine to Solid Tumors: Role of Tumor Physiology (invited)
R.K. Jain, MGH, Harvard Medical School, US (speaker biography)
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10:30 Cancer Prevention, Diagnosis and Treatment through NanotechHall D
 Session chair: Mansoor Amiji, Northeastern University
10:30 Cancer Challenges and the Role of Nanotechnology (invited)
M. Seiden, Massachusetts General Hospital Cancer Center, US
11:00 Nanodelivery: Materializing the Potential of Cancer Molecular Medicine (invited)
E. Chang, Georgetown University, US (speaker biography)
11:30 Novel Nanostructures for Tumor-Targeted Delivery (invited)
D.E. Discher, University of Pennsylvania, US (speaker biography)
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1:30 Cancer Prevention, Diagnosis and Treatment through NanotechHall D
 Session chair: Mansoor Amiji, Northeastern University
1:30 Early Cancer Detection Using Nanowires (invited)
F. Patolsky, Harvard Medical School, US
2:00 Molecular Imaging in Cancer (invited)
J. Basilion, Case Western Reserve Univesity, US
2:30 Targeted Drug Delivery in Cancer (invited)
V. Torchilin, Northeastern University, US
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3:30 Nanotechnology for Cancer Prevention, Diagnosis and TreatmentHall D
 Session chair: Mansoor Amiji, Northeastern University
3:30 Multifunctional Nanoparticles in Cancer Therapy (invited)
S. Bhatia, Massachusetts Institute of Technology, Brigham & Women’s Hospital, US (speaker biography)
4:00 Combination Thermal Medicine and Drug Delivery in Cancer (invited)
S. Nahum Goldberg, Harvard Medical School, US
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4:00 Poster Session 2 and Nanotech Exhibit Reception hosted by Feinstein Kean Healthcare, booth #716Expo Hall
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Cancer Nanotech -3Expo Hall
- The Nucleolus and Cellular Stress: Analysis by Coherent Phase Microscopy
V.P. Tychinsky, A.V. Kretyshev, I.V. Klemyashov, I.V. Reshetov, T.V. Vyshenskaya and A.A. Shtil, P.A.Hertsen Moscow Research Oncological Institute, RU
- Enhanced Accumulation of Long-Circulating Liposomes Modified with Nucleosome-Specific Monoclonal Antibody 2c5 in Various Tumors in Mice
T.A. ElBayoumi and V.P. Torchilin, Northeastern University, US
- Computer Model of Cancer Development
I. Barjis, M. Sayar, J. Barjis and W. Amarrai, New York City College of Technology, US
- Assessment of the dielectric properties of drug sensitive and resistant leukaemic cells before and after ion channel blockers using dielectrophoresis
L. Duncan, H. Shelmerdine, H.M. Coley and F.H. Labeed, University of Surrey, UK
- Rapid Detection of Multiple Myeloma using a microfluidic platform
G. Kaigala, J. VanDjinkin, B.J. Taylor, C.J. Backhouse and L.M. Pilarski, University of Alberta, CA
- A novel soluble nano dimension polyhemoglobin-tyrosinase retards the growth of Murine B16F10 Melanoma in mice
B. Yu and T.M.S. Chang, McGill University, CA
- Characterization and In Vivo Biodistribution Studies with Poly(Ethylene Glycol)-Modified Thiolated Gelatin Nanoparticles
S. Kommareddy and M.M. Amiji, Northeastern University, US
- Utilizing the Electronic Industry‘s Tricks for Transistor Fabrication for Development of New Delivery Vehicles for Nanomedicine Applications
L.E. Euliss, C.M. Welch, B.W. Maynor, S.E. Gratton, J-Y Park, A.A. Pandya, E. Enlow, R.L. Juliano, K.M. Hahn and J.M. DeSimone, University of North Carolina at Chapel Hill, US
- Injection of Molecules into Cells using a pH-Triggered Molecular Nanosyringe
O.A. Andreev, S. Sandugu, D.M. Engelman and Y.K. Reshetnyak, University of Rhode Island, US
- Nano-structured Biodegradable Ceramics for the Prevention and Treatment of Bone Caner
G. Balasundaram and T.J. Webster, PURDUE UNIVERSITY, US
- Mathematical Modeling of Chemotherapy Strategies in Vascular Tumor Growth using Nanoparticles
S. Mishra, V.K. Katiyar and V. Arora, Indian Institute of Technology, Roorkee, IN
- Tumour gene delivery -transfection efficiency and uptake process of Pegylated poly-L-lysine nanoparticles
M. Walsh, M. Tangney, J.O. Larkin, R. Darcy, G.C. O’Sullivan and C.M. O’Driscoll, University College Cork, IE
- Application of Nanomagnetic Particles in Hyperthermia Cancer Treatment
S. Hayek, C-J Chen, Y. Haik and V. Hohite, Florida State University, US
- New manganite-based mediators for self-controlled magnetic hyperthermia
O.A. Shlyakhtin, Y-J Oh, V.G. Leontiev and A.A. Kuznetsov, Institute of Biochemical Physics, Russian Academy of Sciences, RU
- Laser Heating of Sulphuretted Carbon Nanoparticles Inhibits Tumor Growth
B.Ya. Kogan, R.I. Yakubovskaya, A.A. Pankratov, T.N. Andreeva, L.D. Kvacheva, A.A. Titov, V.A. Puchnova, R.A. Feysulova and G.N. Vorozhtsov, Organic Intermediates & Dyes Institute, RU
- Cu-Ni alloy magnetic nanoparticles for hyperthermia at prescribed temperature
A.A. Kuznetsov, V.G. Leontiev, V.A. Brukvin, B.Ya. Kogan, O.A. Kuznetsov and O.A. Shlyakhtin, Institute of Biochemical Physics, Russian Academy of Sciences, RU
- Functionalization of Magnetite (Fe3O4) Nanoparticles for Cancer Treatment
A.P. Herrera, H.L. Rodríguez, M. Torres-Lugo and C. Rinaldi, University of Puerto Rico-Mayagüez, US
- Radioactive Nanocomposite Mouse Tumor Treatment
M.K. Khan, S.S. Nigavekar, L. Minc, B.M. Nair, M.S.T. Kariapper, W.G. Lesniak and L.P. Balogh, Roswell Park Cancer Institute, US
- Magnetic nanoparticle vectors: A tool for diagnosis and therapy
D. Nagesha, R. Sawant, P. Parimi, E. Gultepe, R. Bindra, V. Torchilin and S. Sridhar, Northeastern University, US
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6:00 Translation of Cancer Nanotechnology - From Bench to Bedside (Panel)Hall D
 Session chair: Mansoor Amiji, Northeastern University
- NCI Nanotechnology for Cancer AllianceP. Grodzinski, National Cancer Institute, US
- Role of Nanotechnology Characterization LaboratoryS. McNeil, National Cancer Institute, US
- Role of National Institute of Standards and TechnologyA. Plant, National Institute of Standards and Technology, US
- Role of the Food and Drug AdministrationN. Sadrieh, Food and Drug Administration, US
 

Wednesday May 10

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10:30 Cancer Nanotech - 2Room 207
 Session chair: Mansoor Amiji, Northeastern University, US
10:30 Development of peptide conjugated Superparamagnetic Iron Oxide (SPIO) Nanoparticles for Targeted MR Imaging and Therapy of Pancreatic Cancer
L. Yang, H. Mao, Z. Cao, A. Wang, X. Peng, X. Wang, P. Karna, G. Adams, Q. Yuan, C. Staley, W.C. Wood, S. Nie and X. Gao, Emory University, US
10:50 Development of Tumor Targeting Magnetic Nanoparticles for Cancer Therapy
R. Ivkov, S.J. DeNardo, L.A. Miers, A. Natarajan, A.R. Foreman, C. Gruettner, G.N. Adamson and G.L. DeNardo, Triton BioSystems, Inc., US
11:10 Analysis of Magnetic Particle Capture in the Microvasculature
E.P. Furlani, K.C. Ng and Y. Sahoo, University at Buffalo, US
11:30 Condensation of Therapeutic Oligodeoxynucleotides and Plasmid DNA with PPI Dendrimers and PPI-Modified Gold Nanoparticles
A.M. Chen, S.K. Nair, T.T. Thomas, T.J. Thomas and H. He, Rutgers Unverisity, Newark, US
11:50 Detection of Live Breast Cancer Cells Using Carbon Nanotube Devices
K. Teker, G. Cesarone, E. Wickstrom and B. Panchapakesan, Frostburg State University, US
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1:30 Nanotechnology for Drug DeliveryRoom 208
 Session chair: Mansoor Amiji, Northeastern University, US
1:30 Nanotechnology for Drug Delivery: An Overview (invited overview presentation)
M.M. Amiji, Northeastern University, US
2:00 The Targeted Drug Delivery of Doxorubicin
W.M. Saltzman, T. Fahmy and P.M. Fong, Yale University, US
2:20 Nanoconjugates of poly(malic acid) with functional modules for drug delivery
J.Y. Ljubimova, M. Fujita, B.-S. Lee, N.M. Khazenzon, S. Wachsmann-Hogiu, D.L. Farkas, K.L. Black and E. Holler, Cedars-Sinai Medical Center, US
2:40 Improved Therapeutic Efficacy of Doxorubicin-Loaded Long-Circulating Liposomes Targeted with Anti-Nuclesome Monoclonal Antibody 2C5 Against Various Tumors
T.A. ElBayoumi and V.P. Torchilin, Northeastern University, US
3:00 In Vivo Tracking of Liposomes Using CT and MR Imaging
J. Zheng, J. Liu, D.A. Jaffray and C. Allen, University of Toronto, CA
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4:00 Nanotech for NeurologyRoom 204
 Session chair: Gabriel Silva, University of California, San Diego, US
4:00 Fluorescent Nanoparticle Quantum Dots for Targeted Neuromodulation and Bioassay (invited)
T.Q. Vu, S. Golledge and S.S. Rajan, Oregon Health and Sciences University, US
4:20 Nanotechnology Contributions to Neuroscience and Neurology (invited)
G.A. Silva, University of California, San Diego, US
4:40 Quantum Dot Probes for Tracking Nerve Growth Factor Ligand-Receptor Dynamics in Live Neurons (invited)
S. Sundara Rajan and T.Q. Vu, Oregon Health and Science University, US
5:00 Neuroimaging Distribution of Water Molecules in Brain
E. Vaganova, S. Yitzchaik, H. Ovadia, J.W. Borst, A. Visser, M. Sigalov and V. Khodorkovsky, The Hebrew University, IL
5:20 Three-Dimensional Reconstruction of the Florid Plaque in variant Creutzfeldt-Jakob Diseases
M. Zubert, M. Napieralska, A. Napieralski, B. Sikorska, P. Liberski and R. Grams, Technical University of Lodz, PL
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4:00 Characterization: Drug DeliveryRoom 210
 Session chair: Pierre Panine, E.S.R.F., FR and Greg Haugstad, University of Minnesota, US
4:00 Drug Eluting Coatings for Medical Devices: Multi-Method Characterization (invited)
K. Wormuth and G.D. Haugstad, SurModics Inc., US (speaker biography)
4:30 Sensing and Plotting Single Molecule Binding Events with the Atomic Force Microscope
W.T. Johnson, Molecular Imaging, US
4:50 Dicationic gemini surfactant gene delivery complexes contain cubic-lamellar mixed polymorphic phase
M. Foldvari, S. Wettig, I. Badea, R. Verrall and M. Bagonluri, University of Saskatchewan, CA
5:10 The micro and nano scale characterization of polymer coated drug delivery stents
M. Wu, M.C. Davies and C.J. Roberts, University of Nottingham & Guidant Corporation, UK
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6:00 Poster Session 3 and ReceptionHall D
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Characterization: Drug DeliveryHall D
- Interaction between PEO-PPO-PEO Block Copolymer and Bovine Serum Albumin by FTIR Spectroscopy
C. Guo, J. Wang and H. Liu, Chinese Academy of Sciences, CN
- Interaction between Artificial Mucin Layer and Stimuli-Responsive Nanogel Particles for the Oral Peptide Delivery Observed in Simulated Intestinal Solutions by Using Colloid Probe AFM Method
H. Kamiya, M. Yoshimura, M. Tsukada, H. Ichikawa and Y. Fukumori, Tokyo University of Agriculture and Technology, JP
- Formulation Parameters and Characterization of Drug-loaded Biodegradable Polymeric Nanoparticles
B.J. Nehilla and T.A. Desai, Boston University, US
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Drug DeliveryHall D
- Mitotic Inhibition by Varying the Frequency of Water Clusters
B. Ahern and C. Firestone, Nanocide Technologies Corp, US
- Development of a Novel Triblock Copolymer Therapeutic Nanoreactor
A. Ranquin, C. De Vocht, W. Meier, J. Steyaert and P. Van Gelder, VUB, BE
- Shell Cross-Linked Nanoparticle Based on Poly(e-caprolactone)-Poly(ethylene glycol) for Photosensitizer Delivery
P.S. Lai, M.Y. Huang, S.J.J. Wang, C.N. Chen and M.J. Shieh, National Taiwan University, TW
- Formulation Optimization for the Nanoparticles-in-Microsphere Hybrid Oral Delivery Systems Using Factorial Design
M.D. Bhavsar, S.B. Tiwari and M.M. Amiji, Northeastern University, US
- Cationic Nanoparticles based on pH Responsive Polyion Complexes containing Plasmid GFP DNA
G. Harper and R. Gibbs, WetaScience, UK
- Microscopic Mechanism of Sonoporation
P.A. Prentice, J.M. Burns, A. Cuschieri and P.A. Campbell, University of Dundee, UK
- Creating ‘Smart’ Delivery Systems: Double-Targeted pH-Responsive Pharmaceutical Nanocarriers
R.M. Sawant, J.P. Hurley, S. Salmaso, A. Kale, E. Tolcheva, T.S. Levchenko and V.P. Torchilin, Northeastern University, US
- A Novel Biodegradable System Based on BSA/PCL Core-shell Structured Nanofibers for Controlled Drug Delivery
Y. Feng, Y.Z. Zhang, T. Yong and S. Ramakrishna, National University of Singapore, SG
- Synergistic Release of DNA from pH Responsive Polyion Complexes (PICs)
G. Harper, WetaScience, UK
- Prospects of Anionic Nanolipoplexes Prepared by the Heating Method in Nanotherapy
M.R. Mozafari, C.J. Reed and C. Rostron, Massey University, NZ
- A review: Drug delivery by surfactants
M. Nadeem and I.B. Tan, UNIVERSITI TEKNOLOGI PETRONAS, MALAYSIA, MY
- Synthesis and Photodynamic Efficacy of PAMAM-Photosensitiser Conjugates in Vitro
C.L. Peng, P.S. Lai, C.H. Chiu, C.C. Chang, T.-Y. Lai and M.J. Shieh, National Taiwan University, TW
- Targeting Human Brain Tumor with Anti-Nucleosome Antibody 2C5-modified Liposomes in Nude Mice Model
B. Gupta, T.S. Levchenko, D.A. Mongayt and V.P. Torchilin, Northeastern University, US
- Functional Stimuli-Responsive Nanogel-particles for Oral Peptide Delivery: Preparation, Drug-Release Behaviors and in Vitro Cellular Interaction
H. Ichikawa, Y. Fukumori and H. Kamiya, Kobe Gakuin University, JP
- Construction of Enzymosomes: Optimization of Coupling Parameters
C.A. Vale, M.L. Corvo, L.C.D. Martins, C.R. Marques, G. Storm, M.E.M. Cruz and M.B.F. Martins, Laboratorio Nacional de Engenharia, Tecnologia e Inovacao, IP, PT
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Cellular and Molecular DynamicsHall D
- Modeling of Cellular Communication
I. Barjis, W. Samarrai, I. Augustin and J. Barjis, New York City College of Technology, US
- Nanoscale imaging and mechanical testing of cells and tissues
X. Li, University of South Carolina, US
- Cell proliferation and differentiation on synthetic nanofibrillar surface
M.A. Lodhi, G.W. Opperman and S.M. Larkin, SurModics, Inc., US
- DNA Hybridization
G. Vezzoli, New Hampshire Community Technical College, US
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ImagingHall D
- A highly sensitive fluorescent immunoassay based on avidin labeled nanocrystals
K-K Sin, C.P-Y Chan, T-H Pang, M. Seydack and R. Renneberg, The Hong Kong University of Science and Technology, HK
- Change of 7Be decay rate in exohedral and endohedral C60 fullerene
A. Ray, P. Das, S.K. Saha, J.J. Das and N. Madhavan, Variable Energy Cyclotron Center, IN
- CdSe Nanoparticles Modified with Water-soluble Terpolymers and their Application to Biomarkers
H. Tsutsumi, M. Yamada and M. Yasui, Yamaguchi University, JP
- New Applications of Nanoparticles in Cardiovascular Imaging
R.R. Sharma, FAMU-FSU College of Engineering, US
- Surface Plasmon Spectral Shifts of Functionalized Gold Nano particles for the Use in Biosensors
S. Chatterjee, G. Moriarty and B. Gersten, Queens College, CUNY, US
- The Interaction of Protein-Modified Nanodiamond with Bacterial Cells
E.V. Perevedentseva, J.-S. Tu, C.-Y. Cheng, P.-H. Chung, H.-H. Chang and C.-L. Cheng, National Dong-Hwa University, TW
- Rapid Isolation of AMI Markers using Nanomagnetic Particles
Y. Haik, R. Sista, A. Qablan, C-J. Chen and S. Palanki, United Arab Emirates university, AE
- Polymeric Magnetomicelles As a Probe for MRI Imaging: Characterization and Mri Properties
R.M. Sawant, D. Nagesha, S. Sridhar and V.P. Torchilin, Northeastern University, US
 

Welcome

NSTI is proud to collaborate with the National Cancer Institute (NCI) in presenting a Special Symposium on Nanotechnology for Cancer Prevention, Diagnosis and Treatment.

Towards the end of eliminating suffering and death from cancer, the National Cancer Institute is engaged in efforts to harness the power of nanotechnology to radically change the way we diagnose, image and treat cancer. The NCI-NSTI Nanotechnology for Cancer Special Symposium will run in parallel with the Nanotech 2006 and the BioNano 2006 providing a unique multidisciplinary environment directed towards addressing the challenges of cancer research and treatment.

Video Journey Into Nanotechnology

Watch Video Journey Into Nanotechnology (provided courtesy of NCI)

Synopsis

Nanotechnology has the potential to have a revolutionary impact on cancer diagnosis and therapy. It is universally accepted that early detection of cancer is essential even before anatomic anomalies are visible. A major challenge in cancer diagnosis in the 21st century is to be able to determine the exact relationship between cancer biomarkers and the clinical pathology, as well as, to be able to non-invasively detect tumors at an early stage for maximum therapeutic benefit. For breast cancer, for instance, the goal of molecular imaging is to be able to accurately diagnose when the tumor mass has approximately 100-1000 cells, as opposed to the current techniques like mammography, which require more than a million cells for accurate clinical diagnosis.

In cancer therapy, targeting and localized delivery are the key challenges. To wage an effective war against cancer, we have to have the ability to selectively attack the cancer cells, while saving the normal tissue from excessive burdens of drug toxicity. However, because many anticancer drugs are designed to simply kill cancer cells, often in a semi-specific fashion, the distribution of anticancer drugs in healthy organs or tissues is especially undesirable due to the potential for severe side effects. Consequently, systemic application of these drugs often causes severe side effects in other tissues (e.g. bone marrow suppression, cardiomyopathy, neurotoxicity), which greatly limits the maximal allowable dose of the drug. In addition, rapid elimination and widespread distribution into non-targeted organs and tissues requires the administration of a drug in large quantities, which is often not economical and sometimes complicated due to non-specific toxicity. This vicious cycle of large doses and the concurrent toxicity is a major limitation of current cancer therapy. In many instances, it has been observed that the patient succumbs to the ill effects of the drug toxicity far earlier than the tumor burden.

This symposium will address the potential ways in which nanotechnology can address these challenges. Distinguished speakers will summarize the current state of the art and future barriers. Contributions are also solicited in the following topics.

Topics and Applications

  • Science and technologies for cancer diagnostic and imaging techniques using nanoparticles as reporter platforms and contrast enhancing agents;
  • Bionalaytical nanotechnology for detection of biomarkers
  • Nanoparticle platforms polymeric nanoparticles, lipid nanoparticles, metal nanoparticles, magnetic nanoparticles, and self-assembling nanosystems;
  • Synthetic chemistry required to design and optimize new strategies for nanoparticle preparation and functionalization;
  • Therapeutic targeted and intra-cellular drug and gene delivery using nanocarriers;
  • Nanoparticles for delivery of electromagnetic energy for hyperthermia and thermal ablation of tumors;
  • Theoretical modeling of nanoparticle processes in biological and medical environments, and of drug and gene delivery;
  • Combination therapies (drug and energy delivery) using nanoparticles
  • Clinical diagnosis and therapy of prostate, breast, and liver cancer.

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Journal Submissions

Journal of Nanoparticle Research

Journal of Nanoparticle Research

Selected Nanotech Proceedings papers will be reviewed and invited into a Special Issue of Journal of Nanoparticle Research.

For consideration into this Special Issue of Journal of Nanoparticle Research, please select the "Submit to Journal of Nanoparticle Research" button during the on-line submission procedure. Please note that you may only select a single journal during the submission process.

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2005 Speakers Included

Gregory J. Downing
Director, Office of Technology and Industrial Relations, National Cancer Institute
(speaker biography)
Nanoparticles in Cell Imaging
John V. Frangioni, Beth Israel Deaconess Medical Center, Harvard University
(read more)
Mansoor Amiji
Department of Pharmaceutical Sciences, Northeastern University, US
Vladimir Torchilin Vladimir Torchilin
Bouvé College of Health Sciences, Northeastern University
Mauro Ferrari Mauro Ferrari
Davis Heart & Lung Research Institute, Ohio State University
(speaker biography)
Paul Alivisatos New Nanocrystal Assemblies for Use in Cancer Research
Paul Alivisatos, University of California Berkeley
(speaker biography)
Peter E. Barker Semiconductor Nanocrystal Probes for Human Chromosomes
Peter E. Barker, National Institute of Standards and Technology
Dennis Carson Dennis Carson
Rebecca and John Moores UCSD Cancer Center, University of California, San Diego
(speaker biography)

In Association with

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ICCN 2006 2006 NSTI Nanotechnology Conference and Trade Show
Nanotech 2006
ICCN 2006 2006 International Conference on Computational Nanoscience and Nanotechnology
ICCN 2006
CCE 2006 2006 International Conference on Clean & Controlled Environments
CCE 2006
MSM 2006 Eighth International Conference on Modeling and Simulation of Microsystems
MSM 2006
WCM 2006 2006 Workshop on Compact Modeling
WCM 2006
BioNano 2006 2006 NSTI Bio Nano Conference and Trade Show
BioNano 2006

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