Nanotechnology Conference and Trade Show - Nanotech 2006
> Program > Technical Conferences > Business & Development > Nano Impact Workshop > Nanotech Job Fair > Expo
Program
Sessions
Sunday
Monday
Tuesday
Wednesday
Thursday
Index of Authors
Index of Keywords
Confirmed Speakers
Conferences & Symposia

Conference Proceedings

Conference Technical Proceedings

Drug Eluting Coatings for Medical Devices: Multi-Method Characterization

K. Wormuth and G.D. Haugstad
SurModics Inc., US

Keywords:
drug eluting coatings, medical devices, multi-method characterization

Abstract:
Drug eluting stents, cage-like metal devices coated with a drug/polymer mixture, significantly advance the treatment of cardiovascular disease. The metal cage keeps weakened blood vessel walls open and the polymer coating elutes a drug which prevents scar tissue formation (restenosis) which can re-block the vessel. Formulation of drug eluting coatings remains a challenge since the coating must be thin and conformal, the polymer matrix must be tailored to incorporate high concentrations of drug and to control the elution of the drug, and the coating must withstand the severe deformations of the metal cage upon insertion into the vessel. Polymer blend coatings often offer advantages not found in single polymer coatings: ability to tune drug elution rates and mechanical properties by varying the ratio of the two polymers. Here we apply multiple techniques to probe coating morphology from the interior to the outer surface and from the micro- down to the nanoscale: light, infrared, Raman, scanning electron and scanning probe microscopies. In our scanning probe studies, we exploit the digital pulsed force mode (DPFM) to probe chemical and mechanical properties of the coating surfaces at the nanoscale.

Back to Program

Sessions Sunday Monday Tuesday Wednesday Thursday Authors

Nanotech 2006 Conference Program Abstract

 
Nanotechnology Conference | Terms of use | Privacy policy | Contact | NSTI Home
Program | Technical Conferences | Business & Development | Nano Impact Workshop | Nanotech Job Fair | Expo |
Nanotech 2006 Home | Press Room | Venue | Subscribe | Site Map
Names, and logos of other organizations are the property of those organizations and not of NSTI.
This event is not open to the general public and NSTI reserves the right to refuse admission and participation to any individual.