Nanotechnology Conference and Trade Show - Nanotech 2006
> Program > Technical Conferences > Business & Development > Nano Impact Workshop > Nanotech Job Fair > Expo
Program
Sessions
Sunday
Monday
Tuesday
Wednesday
Thursday
Index of Authors
Index of Keywords
Confirmed Speakers
Conferences & Symposia

Conference Proceedings

Conference Technical Proceedings

Simulation of a Microfluidic Particle Concentrator and Separator

C.-C. Chen and G.W. Auner
Industrial Technology Research Institute, TW & Wayne State University, US

Keywords:
flow-through reactor, polymerase chain reaction (PCR), thermocycling, microchannel, lab-on-a-chip, multiphysics simulation

Abstract:
A flow-through micro polymerase chain reaction (PCR) chip was optimized by using coupled multiphysics computational tools. Comprehensive simulations of temperature and flow profiles were presented for the denaturation, extension, and annealing zones on the flow-through thermocycling chip with ANSYS. The flow simulation shows that the room temperature fluid in the 100 um deep microchannels reached the designated temperature after traveling a few hundred um at the flow rate of 140nl/s. The air gaps between the heating blocks were found to be at least 1mm for proper thermal isolation. The joule heating simulation of the initial design shows a drop of 1.6ºC on both ends of the long heating blocks due to the larger convection on the ends, as well as the less heating efficient aluminum conducting pads and the non-uniform current at the U-turn. After heating compensation by locally alternating the heater patterns, we achieved a perfect flat temperature profile over the 50 mm span of heating blocks.

Back to Program

Sessions Sunday Monday Tuesday Wednesday Thursday Authors

Nanotech 2006 Conference Program Abstract

 
Nanotechnology Conference | Terms of use | Privacy policy | Contact | NSTI Home
Program | Technical Conferences | Business & Development | Nano Impact Workshop | Nanotech Job Fair | Expo |
Nanotech 2006 Home | Press Room | Venue | Subscribe | Site Map
Names, and logos of other organizations are the property of those organizations and not of NSTI.
This event is not open to the general public and NSTI reserves the right to refuse admission and participation to any individual.