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Symposium on

Bio Molecular Analysis

Symposium Chair: Srinivas Iyer, Los Alamos National Laboratory

Synopsis

Nanotechnology in the Life-sciences is omnipresent. Several biological systems operate at the nanoscale with remarkable precision and regulation. A fine example is that of biomolecular motor proteins, designed by nature to carry out critical functions in the cell. Most of the properties of these proteins are nanoscale, be they size or time of operation. While systems such as motors have been isolated, modified and studied in detail at the biochemical level, much needs to be done at the level of hybrid structures with interfaces to inorganic materials. Further, scaling laws need to be understood in order to bridge between single molecules and higher order devices or architectures.

A similar situation is encountered with biomaterials, another area with tremendous application potential. Alongwith these topics, this symposium will also cover the equally important area of biomolecular analysis, which has reached new levels of sensitivity, precision and resolution due to advances in other sciences. Thus, topics scuh as fluidics, detection methods and engineering approaches will receive enhanced attention. Drug design and delivery is poised the interface of several topics such as receptor signaling, computational modeling, targeted design, nanoscale biomaterials and toxicological profiles.

We invite submissions in each of these areas and related topics. A sample listing of pertinent topics is listed below. This is by no means an exclusive list, but aims to give a general overview of this diverse symposium topic.

Contact siyer@lanl.gov with questions/comments.

Topics and Applications

  • Bio Molecular Motors
    • Device integration
  • Nanobiomaterials
    • Tissue engineering
    • Membranes, Filtration and Separation
  • Fluidics
    • Preconcentration
    • PCR workflows
    • Interfaces with MS and other detection methods
    • Nanoscale separations: advantages and pitfalls
    • Electrophoresis
    • Flow Cytometry
    • Liquid Chromatography
    • Lab-on-Chip
  • Detection
    • Mass Spectrometry : quantitation issues
    • Spectroscopy and Imaging
    • Advanced image analysis routines and algorithms
    • Surface Plasmon Resonance
    • Bio Markers, Nano Particles and Q-Dots functionalization
    • Fluorescence
    • Electrochemical
  • Applications in health
    • Drug design and delivery
    • Target Discovery and Validation
    • DNA, Protein, Cells and Tissue Arrays
    • Toxicology Studies
    • Cell Signaling Pathways
    • Computer-aided high-throughput ligand design
    • Novel high-throughput chemical synthesis and screening
    • Diagnostic tools
    • Portable, economical assays
    • Ethical considerations
    • Validation methods
 
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