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Effect of High AC Magnetic Field on Magnetic Nanoparticles for Magnetic Hyperthermia and Radiation/Chemotherapy Applications

D. Belc, C. Chen, R. Roberts, M. Bettge, R. Arora and V. Mohite
Florida State University, US

Keywords:
magnetic hyperthermia, magnetic heating, tumor

Abstract:
There are numerous studies in the field that explain and model the behavior and heating properties of magnetic nanoparticles (NPs) when exposed to an alternating magnetic field [1, 2]. Particularly for applications such as magnetic hyperthermia and chemotherapy, where high synergies have been noted [x ref/table, and 14mhz], NPs magnetic heating is of great importance and interest. The NPs are used as magnetically controlled nano-thermoseeds. These and other studies have shown significant NPs temperature increase at frequencies well above 50kHz to 10MHz [3-5]. However, little emphasis is given to the NP magnetic heating behavior under 50kHz. This study investigates the NP heating due to an alternating magnetic field for magnetic hyperthermia applications at frequencies below 50kHz. Two different composite materials are investigated.

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