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Nano Science and Technology Institute 2004 NSTI Nanotechnology Conference & Trade Show
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Biophan Technologies, Inc.

M. Weiner
Biophan Technologies, Inc., US

Keywords: Bridging Commercial Applications of Nano-BioTechnology

Abstract:
Biophan Technologies, Inc. (OTC BB: BIPH) develops nanomagnetic materials for biomedical devices. The Company has recently licensed new technology for use of these materials as contrast agents for MRI diagnostics. These materials are intended to provide improvements in image contrast over existing products and may also permit multiple disease states to be image-enhanced during a single MRI procedure. These materials stem from coatings that the Company has been developing to reduce image artifacts and enhance the visibility of many biomedical devices, both implantable and interventional, that today are difficult to image under MRI due to eddy currents and other problems that interfere with MRI imaging. The coatings can also improve the ability to image guidewires and devices used in many surgical procedures. Contrast agents represent an extension of the underlying technology. Biophan has solutions that can enable devices contraindicated for MRI due to safety concerns_devices such as pacemakers, defibrillators, neurostimulators, guidewires, endoscopes, etc. Safety problems usually involve device heating and, in some cases, induced voltages that can cause very rapid heartbeats. Biophan has developed a tool kit of solutions that allows biomedical device manufacturers to resolve the specific problems that cause devices to have difficulties undergoing successful MRI procedures. Biophan holds an exclusive license from Johns Hopkins for an MRI Safe Pacemaker and ECG Lead using an RF filter that has been successfully tested on pacemaker leads; an exclusive license from Nanoset for medical rights to thin-film nanomagnetic particle coatings that provide a magnetic shield without electrical conductivity; and exclusive rights to a carbon composite material developed at the University of Buffalo. Biophan has four issued patents and over 50 patents pending, relating to MRI safety, image compatibility, and enhanced MRI imaging.

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